{"id":27423,"date":"2020-12-04T05:00:32","date_gmt":"2020-12-04T05:00:32","guid":{"rendered":"https:\/\/pr.asianetpakistan.com\/?p=67856"},"modified":"2020-12-04T05:00:32","modified_gmt":"2020-12-04T05:00:32","slug":"taconic-biosciences-expande-o-portfolio-expressmodel-inovador","status":"publish","type":"post","link":"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/","title":{"rendered":"Taconic Biosciences Expande o Portf\u00f3lio ExpressMODEL\u00ae Inovador"},"content":{"rendered":"

Nova solu\u00e7\u00e3o de gera\u00e7\u00e3o de modelo animal transg\u00eanico de integra\u00e7\u00e3o aleat\u00f3ria dispon\u00edvel<\/h4>\n

RENSSELAER, Nova York, Dec. 03, 2020 (GLOBE NEWSWIRE) — A Taconic Biosciences, l\u00edder global no fornecimento de solu\u00e7\u00f5es de modelo de animais para a descoberta de medicamentos, anuncia o lan\u00e7amento do novo servi\u00e7o\u00a0ExpressMODEL<\/u><\/a>\u00ae<\/u><\/a>:<\/u><\/a>\u00a0Random Integration Transgenic\u00a0<\/u><\/a>(<\/u><\/a>RITg<\/u><\/a>)<\/u><\/a>\u00a0(Transg\u00eanico de Integra\u00e7\u00e3o Aleat\u00f3ria), que reduz os custos de gera\u00e7\u00e3o e o cronograma de modelo animal.<\/p>\n

Muitas tecnologias de edi\u00e7\u00e3o de genes s\u00e3o usadas para gerar modelos animais para a descoberta de drogas, cada uma com considera\u00e7\u00f5es \u00fanicas, mas com o objetivo compartilhado de criar perfis gen\u00e9ticos espec\u00edficos. A t\u00e9cnica usada para gerar modelos RITg resulta em uma ninhada inicial onde os animais fundadores individuais podem ou n\u00e3o transportar e\/ou expressar a caracter\u00edstica gen\u00e9tica pretendida. Tradicionalmente, cada animal deve ser criado por muitas gera\u00e7\u00f5es para determinar qual produz o resultado desejado. Este processo adiciona tempo e dinheiro consider\u00e1veis a um projeto. Em uma ind\u00fastria for\u00e7ada a reduzir cronogramas e custos para o lan\u00e7amento de novas terap\u00eauticas em todo o mundo, a ExpressMODEL\u00ae: A RITg diminui essa press\u00e3o.<\/p>\n

Em vez de reproduzir cada animal fundador e caracterizar sua prole, a ExpressMODEL\u00ae: A RITg analisa a express\u00e3o do transgene e a fertilidade animal na primeira ninhada. Esta abordagem reduz os v\u00e1rios riscos inerentes \u00e0 gera\u00e7\u00e3o do modelo RITg. Em primeiro lugar, reconhecer os animais de sucesso mais cedo elimina o desperd\u00edcio de recursos com a cria\u00e7\u00e3o de animais com perfis gen\u00e9ticos incorretos. Em segundo lugar, a obten\u00e7\u00e3o dos animais corretos no in\u00edcio do processo proporciona previsibilidade para as atividades a jusante. Uma vez que os projetos exigem uma coordena\u00e7\u00e3o intensa com outras partes interessadas e recursos, isso \u00e9 extremamente valioso. Em terceiro lugar, os clientes podem personalizar o tamanho final da coorte e o padr\u00e3o de sa\u00fade animal. Em quarto lugar, a busca de um n\u00famero menor de animais antecipadamente reduz o n\u00famero total necess\u00e1rio para o projeto.<\/p>\n

\u201cO portf\u00f3lio da ExpressMODEL<\/u><\/a> \u00ae<\/u><\/a> teve in\u00edcio com a Taconic aproveitando seus conhecimentos e capacidades de uma nova maneira para acelerar o processo de gera\u00e7\u00e3o de modelos\u201d, compartilhou o Dr. John Couse, vice-presidente de servi\u00e7os cient\u00edficos da Taconic. \u201cO ExpressMODEL\u00ae: RITg d\u00e1 continuidade a esse compromisso, com a combina\u00e7\u00e3o do forte know-how de gera\u00e7\u00e3o de modelos da Taconic com a experi\u00eancia em criopreserva\u00e7\u00e3o de espermatozoides, fertiliza\u00e7\u00e3o in vitro e an\u00e1lise de transgene para eliminar os riscos associados a esta t\u00e9cnica de edi\u00e7\u00e3o de genes. Isso fornece aos clientes dados decisivos meses antes das abordagens convencionais. \u00c9 um caso raro em pesquisas onde os clientes n\u00e3o precisam escolher velocidade ou qualidade.\u201d<\/p>\n

A Taconic \u00e9 uma fornecedora totalmente licenciada de servi\u00e7os de gera\u00e7\u00e3o de modelos de roedores com mais de vinte anos de experi\u00eancia<\/u> com gera\u00e7\u00e3o<\/u> de modelos<\/u><\/a>, fornecendo inativa\u00e7\u00e3o g\u00eanica, muta\u00e7\u00e3o ou substitui\u00e7\u00e3o g\u00eanica, express\u00e3o de transgene, RNAi e edi\u00e7\u00e3o g\u00eanica atrav\u00e9s das tecnologias CRISPR\/Cas9 para garantir que as ferramentas certas sejam utilizadas em cada projeto espec\u00edfico do cliente. Al\u00e9m disso, a Taconic tamb\u00e9m fornece uma transi\u00e7\u00e3o sem problemas desde o design do modelo at\u00e9 a cria\u00e7\u00e3o e gerenciamento de col\u00f4nias<\/u><\/a>, oferecendo assim aos clientes uma solu\u00e7\u00e3o completa. Esses servi\u00e7os cient\u00edficos incluem adquirir ou gerar, importar, licenciar, reproduzir, testar, preparar e distribuir modelos geneticamente modificados para qualquer local do mundo.<\/p>\n

Para mais informa\u00e7\u00f5es sobre as\u00a0Solu\u00e7\u00f5es de Gera\u00e7\u00e3o de Modelos<\/u><\/a>, entre em contato com a Taconic por telefone para 1-888-TACONIC (888-822-6642) nos EUA, +45 70 23 04 05 na Europa, ou email\u00a0info@taconic.com<\/u><\/a>.<\/p>\n

Sobre a Taconic Biosciences, Inc.<\/p>\n

A Taconic Biosciences \u00e9 uma l\u00edder global totalmente licenciada em servi\u00e7os e modelos geneticamente modificados. Fundada em 1952, a Taconic oferece as melhores solu\u00e7\u00f5es \/ modelos de pesquisas em murinos, para que os clientes possam adquirir, customizar, criar, pr\u00e9-condicionar, testar e distribuir valiosos modelos de pesquisa em todo o mundo. Especializada em modelos de camundongos e de ratos geneticamente projetados, microbioma, modelos de camundongos imuno-oncologia, e servi\u00e7os de design e cria\u00e7\u00e3o de modelos integrados, a Taconic opera tr\u00eas laborat\u00f3rios de servi\u00e7os e seis instala\u00e7\u00f5es de cria\u00e7\u00e3o nos EUA e na Europa, mant\u00e9m rela\u00e7\u00f5es com distribuidores na \u00c1sia e tem capacidades de entrega em n\u00edvel global para oferecer modelos em quase qualquer lugar no mundo.<\/p>\n

Contato da M\u00eddia:
\nKelly Owen Grover
\nDiretora de Comunica\u00e7\u00f5es de Marketing
\n(518) 697-3824
\nkelly.grover@taconic.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Nova solu\u00e7\u00e3o de gera\u00e7\u00e3o de modelo animal transg\u00eanico de integra\u00e7\u00e3o aleat\u00f3ria dispon\u00edvel RENSSELAER, Nova York, Dec. 03, 2020 (GLOBE NEWSWIRE) \u2014 A Taconic Biosciences, l\u00edder global no fornecimento de solu\u00e7\u00f5es de modelo de animais para a descoberta de medicamentos, anuncia o lan\u00e7amento do novo servi\u00e7o\u00a0ExpressMODEL\u00ae:\u00a0Random Integration Transgenic\u00a0(RITg)\u00a0(Transg\u00eanico de Integra\u00e7\u00e3o Aleat\u00f3ria), que reduz os custos de [\u2026]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31],"tags":[],"yoast_head":"\nTaconic Biosciences Expande o Portf\u00f3lio ExpressMODEL\u00ae Inovador - South Africa Journal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Taconic Biosciences Expande o Portf\u00f3lio ExpressMODEL\u00ae Inovador - South Africa Journal\" \/>\n<meta property=\"og:description\" content=\"Nova solu\u00e7\u00e3o de gera\u00e7\u00e3o de modelo animal transg\u00eanico de integra\u00e7\u00e3o aleat\u00f3ria dispon\u00edvel RENSSELAER, Nova York, Dec. 03, 2020 (GLOBE NEWSWIRE) \u2014 A Taconic Biosciences, l\u00edder global no fornecimento de solu\u00e7\u00f5es de modelo de animais para a descoberta de medicamentos, anuncia o lan\u00e7amento do novo servi\u00e7o\u00a0ExpressMODEL\u00ae:\u00a0Random Integration Transgenic\u00a0(RITg)\u00a0(Transg\u00eanico de Integra\u00e7\u00e3o Aleat\u00f3ria), que reduz os custos de [\u2026]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/\" \/>\n<meta property=\"og:site_name\" content=\"South Africa Journal\" \/>\n<meta property=\"article:published_time\" content=\"2020-12-04T05:00:32+00:00\" \/>\n<meta name=\"author\" content=\"sjadmin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"sjadmin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/\"},\"author\":{\"name\":\"sjadmin\",\"@id\":\"https:\/\/southafricajournal.com\/#\/schema\/person\/b5258049232dc72b42ad1073df5c990f\"},\"headline\":\"Taconic Biosciences Expande o Portf\u00f3lio ExpressMODEL\u00ae Inovador\",\"datePublished\":\"2020-12-04T05:00:32+00:00\",\"dateModified\":\"2020-12-04T05:00:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/\"},\"wordCount\":800,\"publisher\":{\"@id\":\"https:\/\/southafricajournal.com\/#organization\"},\"articleSection\":[\"Press Releases\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/\",\"url\":\"https:\/\/southafricajournal.com\/taconic-biosciences-expande-o-portfolio-expressmodel-inovador\/\",\"name\":\"Taconic Biosciences Expande o Portf\u00f3lio ExpressMODEL\u00ae Inovador - 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